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A known history of pancreatitis
Potential adverse effects and drug interactions: Gastrointestinal symptoms Cramping, diarrhoea, constipation, and abdominal discomfort are common, particularly at higher doses
Approximately two-thirds of participants maintained a substantial degree of weight loss (less than 5% regain from their lowest weight) over this period
This is the primary driver of GLP-1 weight regain
It is neither a stronger drug nor a universal upgrade
In turn, this can make experiencing fatigue less likely or, at least, make the fatigue less severe
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