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Sources conflict on whether fosgonimeton is a prodrug of Dihexa or a structurally distinct molecule, so it should not be read as evidence for or against Dihexa specifically only as the nearest human data point in the program, and a negative one

Depletion of essential isoprenoids and ER stress induction following acute liver-specific deletion of HMG-CoA reductase

[8] The rate of weight reduction in test subjects was consistently compared to the placebo cohort, and weight loss appeared to hold steady over the entire study period

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