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Common early side effects include nausea, fullness, mild constipation or diarrhea, and a decreased desire to eat

Trials summarized by Leidy and colleagues show that people on higher-protein, calorie-restricted diets generally lose more fat mass , preserve more lean mass , and report higher fullness than people on lower-protein diets

GLP-1 stands for glucagon-like peptide-1, a hormone released after eating that helps regulate appetite, digestion, and blood sugar

Athletes using semaglutide for approved medical reasons should maintain documentation

However, the proportion of muscle loss is not greater than what occurs with diet alone

Over-the-counter interventions can provide relief while your body adjusts