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Retatrutide is typically studied as a once-weekly injection given under the skin

Biochem 71 , 329340 (2015)

If vomiting persists, talk to your doctor about anti-nausea medications that are safe to use alongside GLP-1 therapy

Another trial that included 150 women with PCOS and impaired glucose tolerance found that combining GLP-1 therapy with metformin led to a 64% remission rate of prediabetes