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Category 2 List
Research confirms it maintains this selectivity even at extremely high dosages, ensuring that experimental observations reflect pure growth hormone signaling rather than multi-hormonal activation This molecular precision is critical for mechanistic research, where hormonal cross-activation, such as stimulation of the hypothalamic-pituitary-adrenal (HPA) axis, would otherwise confound the data
Subsequently, research-oriented stimulation was carried out at frequencies of 1 Hz for 30 s (totalling 30 stimulation pulses) and 10 Hz for 30 s (totalling 300 stimulation pulses) at intensities of 1, 2 and 3 mA at two different depths in the STN, each separated by at least 2 mm vertically
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