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Tricyclic antidepressants like amitriptyline and antiemetics like ondansetron may similarly impair the delayed-gastric-emptying mechanism that GLP-1 agonists leverage for weight and glucose control

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Lilly said most cases involving paresthesia were mild and rarely led to treatment discontinuation

Both medications contain glucagon-like peptide-1 (GLP-1) receptor agonists

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