The peptide does not appear to affect levels of insulin or IGF1 in studies thus far
This overview is educational, not medical advice, so anyone considering a peptide regimen, prescription or non-prescription, should consult a licensed healthcare provider to confirm it's appropriate for their health history
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It is likely that the larger number of statistically significant changes to the microbiome observed in the groups switched from WD to LD reflects their more numerous exposures to different diets, longitudinal changes in dietary exposure, the stress associated with diet switch, the negative energy state achieved by treatment and/or diet-driven weight loss, or a combination of these factors, but it may also be related to differences in terminal body weight and fat mass since both adiposity and diet composition have been shown to modulate the mouse gut microbiome profile