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This isn't because 1:1 is mechanistically optimal in some provable way it's because researchers studying combinations of these compounds chose 1:1 as the default and the literature accumulated around that choice
Mancuso C, Bates TE, Butterfield DA, Calafato S, Cornelius C, De Lorenzo A, Dinkova Kostova AT, Calabrese V: Natural antioxidants in Alzheimer's disease
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232,234 MSC therapy to promote healthy endometrial tissue has also been proposed as a future treatment for endometrial problems related to infertility, such as Asherman syndrome (intrauterine adhesions) and possibly even endometriosis
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