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Oakley AJ, Yamada T, Liu D, Coggan M, Clark AG, Board PG

ZO-3, a novel member of the MAGUK protein family found at the tight junction, interacts with ZO-1 and occludin

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Glutathione is equally important in detoxification pathways , particularly in the liver

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In contrast to M1 macrophages, M2 macrophages secrete anti-inflammatory factors such as IL-10 and TGF- to inhibit the production of inflammatory mediators and MMPs, and they can also clear free hemoglobin and regulate oxidative stress, which will promote vascular remodeling and repair (288, 293)