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Contraindications for Janumet XR JANUMET XR is contraindicated in patients with: Severe renal impairment (eGFR below 30 mL/min/1.73 m) [see WARNINGS AND PRECAUTIONS ]

This route provides consistent absorption and suits self-administration

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Purification, properties, and mechanism of action [PMID: 6035915] Laboratory literature summary: Tripeptide (glutathione) synthetase