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Available from: Konjevod M, Nedic Erjavec G, Nikolac Perkovic M, Siz J, Tudor L, Uzun S, et al
Intriguingly, the mechanisms of oxidative phosphorylation-related genes upregulation are cell type specific
Furthermore, another component of the API complex, FOSL1, is highly expressed in IPSC-derived motor neurons from SOD1 patients carrying the E100G mutation (Bhinge et al., 2017) compared to isogenic controls, suggesting that the AP1 complex is a driver for neurodegeneration
Compared to the group with the lowest amount, the group with the second highest amount of acetaminophen was 2.14 times more likely to have ASD, while the group with the highest amount was 3.62 times more likely to have ASD
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