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Descriptions and sources of reagents and detailed methods of our mouse models of experimental MI in vivo (66), IRI in vivo (67), IRI ex vivo (4, 21), as well as mouse and human cellular injury models in vitro (21, 68) are provided in the Supplemental Methods

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(This range varies a little bit, depending on who is defining normal)

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For Peptide Sameness: Accurate mass measurement Fragmentation pattern matching Impurity comparison Synthetic route evaluation Degradation pathway alignment The goal: eliminate structural uncertainty