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1 Animal studies The Wegovy SmPC reports that in pregnant rats given semaglutide, the developing pups showed signs of harm at doses lower than those used to treat obesity in humans
The honest framing is that they are not interchangeable, and the decision should be based on the patients full clinical picture rather than the headline number alone
"Stable gastric pentadecapeptide BPC 157 in trials for inflammatory bowel disease (PL-10, PLD-116, PL-14736, Pliva, Croatia)." Current Pharmaceutical Design
Manfredi Rizzo is former Director, Clinical Medical & Regulatory Department, Novo Nordisk Europe East and South and has given lectures, received honoraria and research support, and participated in conferences, advisory boards and clinical trials sponsored by pharmaceutical industry including Amgen, AstraZeneca, Boehringer Ingelheim, Kowa, Eli Lilly, Meda, Mylan, Merck Sharp & Dohme, Novo Nordisk, Novartis, Roche Diagnostics, Sanofi and Servier
those aged 40 and over with unexplained weight loss and abdominal pain
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