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Second-generation oral semaglutide, whose bioavailability and safety have been significantly improved by the application of new excipients and formulation optimization, but its gastrointestinal side effects are still obvious (Saxena et al., 2023)

Cancer development typically occurs over years to decades

Dimethyl fumarate treatment induces adaptive and innate immune modulation independent of Nrf2

Nausea typically peaks 30 to 60 minutes post-dose and resolves within 2 hours for most patients