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Souza, S
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Plus, real-world adherence data from Blue Health Intelligence and a 2025 study in JAMA Network Open show that roughly 30 percent of patients discontinue within the first month and over half quit within three months with physical discomfort cited as a primary driver. However, with the exception of nausea, Carroll explains that what often tips a patient toward wanting to discontinue the medication isnt one severe symptom
That small addition is the game-changer
For example, patients using GLP-1 or dual agonist medications benefit from eating more slowly, taking smaller bites, and allowing more time between courses
Conclusion VLCD modulated metabolic gene expression and fatty acid profiles, enhancing IR and metabolic health both pre- and post-surgery
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