10.1186/s12974-016-0787-0 67 MerlinJ.IvanovS.DumontA.SergushichevA.GallJ.StunaultM.et al (2021)
Trial status: Active, not recruiting Clinical Trials Identifier: NCT06077864 Trial Name: A Study to Test the Effect of Survodutide (BI 456906) on Cardiovascular Safety in People With Overweight or Obesity (SYNCHRONIZE - CVOT) Diabetes Type: Adults with overweight or obesity who have weight-related health conditions with or without type 2 diabetes Trial Sponsor: Boehringer Ingelheim What is the aim of the study
Each of these trials demonstrated the benefit of combination therapy, whereby combination of an SGLT2i and a RAAS inhibitor reduced the risk of progression or death from CV (or kidney) causes, CV events, and risk of kidney failure compared with RAAS inhibitor/standard of care alone [14,15,16]
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364 Thus, c-MET also represents a target for cancer immunotherapy, with its function in human neutrophils increasingly understood in recent years