Mitochondrial dysfunction in neurodegenerative diseases
Stealth liposomes have demonstrated notable versatility in encapsulating both hydrophilic and lipophilic drugs, protecting them from enzymatic degradation and improving pharmacokinetic metrics such as area under the curve (AUC) and maximum plasma concentration (Cmax) [104,105,106]
Furthermore, uncertainty in accounting for individual patient variability, such as genetic predispositions, disease stage, or coexisting conditions, makes available drugs less effective across diverse patient populations 78
Consequently, experts suggest erring on the side of caution
Acknowledgements We are grateful to Jie Li, Yanyan Chen, Xianyue Chen and Yang Li for technical assistance
Manufacturers will need to understand how changes in consumer behavior will evolve and impact demand for their products and how their strategy and portfolio need to change to react to this (e.g