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Gegen Qinlian decoction relieved DSS-induced ulcerative colitis in mice by modulating Th17/Treg cell homeostasis via suppressing IL-6/JAK2/STAT3 signaling
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They recently conducted an initial phase 1 clinical trial to determine how well humans tolerate the drug
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Combine this with a genetic variant for an enzyme called diamine oxidase (DAO), the main enzyme responsible for metabolizing ingested histamine, and the result is high histamine which can lead to headaches
