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It is advisable to discuss use with a healthcare practitioner to mitigate the risk of adverse interactions

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10.1248/bpb.b13-00778 211 OliverD

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The distinct sequences that tirzepatide and peptide 20 employed, respectively, to recognize GIPR or GLP-1R are obviously different: the former was primarily based on the GIP sequence with engineered GLP-1 activity 15 , whereas the latter was derived from a GLP-1R/GCGR dual agonist in conjunction with GIP agonism 22