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Huang CC, Phan THM, Ooya T, Kawasaki S, Lin BY, Jan JS

Copper increases brain oxidative stress and enhances the ability of 6-hydroxydopamine to cause dopaminergic degeneration in a rat model of Parkinsons disease

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Preclinical studies suggest it modulates nitric oxide pathways and growth-factor expression to promote angiogenesis and collagen deposition in damaged tissues [1] [3]