The activation of the STING/IFN I axis in tumors not only improved the innate cell-dependent efficacy of ICB (162), but was also shown to enhance the efficacy of anti-angiogenic therapies, namely VEGFR2 blockade (161)
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COMT genetics may provide context for catecholamine and catechol-estrogen handling, but actual function also depends on SAM availability, SAH inhibition, magnesium, stress, hormones and other factors
Journal of Agriculture and Food Chemistry, 52 , 55335538