If you dont get enough vitamin B12 or you have low B12 absorption, your body will start to respond
One trial used 2000 g/day vitamin B 12 and demonstrated a mean difference of 680 pg/mL (95% confidence interval 392.7 to 967.3) in favor of oral vitamin B 12
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Does it improve on rest days from your protocol
If levels don't respond to standard supplementation, investigate possible MTHFR polymorphisms, malabsorption conditions like celiac or Crohn's disease, or potential medication interactions