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However, most of the subjects included in the RCTs are PCOS patients with obesity/overweight, whereas a portion of PCOS women, which can even reach 50%, might present a lean phenotype

Several GLP-1 receptor agonists are approved specifically for weight loss in adults, including: Semaglutide (Wegovy)

2007 Sep;1(3):201-7

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The following formula illustrates the relationship: Concentration (mg/mL) = Vial content (mg) Volume of bacteriostatic water added (mL) Illustrative examples: 2 mg vial + 1 mL bacteriostatic water = 2 mg/mL 2 mg vial + 2 mL bacteriostatic water = 1 mg/mL 5 mg vial + 2 mL bacteriostatic water = 2.5 mg/mL Note that the concentrations in the examples above differ from one another

14 First, there is an inherent trade-off between sensitivity and specificity