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This neuroprotection is partly mediated by modulation of NMDA receptor activity and the maintenance of intracellular redox balance (9)
Why: Isotretinoin is derived from vitamin A and combining the two increases the risk of hypervitaminosis A , which can cause: Headaches / pseudotumour cerebri Liver toxicity Nausea Bone pain Skin peeling Mood changes Avoid: Vitamin A capsules Multivitamins containing high-dose retinol Cod liver oil (contains vitamin A) Most multivitamins have Vitamin A with very low levels ( 5,000 mcg
"Maternal vitamin B12 status and risk of neural tube defects in a population with high neural tube defect prevalence and no folic Acid fortification"
S.et al (2012)
PubMed PMID: 23050815
The distinction between occasional heartburn and true GERD matters clinically
