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GLP-1 receptors are also present in the central nervous system, particularly in appetite-regulating centers of the hypothalamus, where activation promotes satiety and reduces food intake

These regions are believed to be involved in many of the non-enzymatic functions of DPP-4, interacting with other proteins, such as adenosine deaminase, caveolin-1, streptokinase and plasminogen, and with components of the extracellular matrix (collagen, fibronectin), as well as functioning as binding sites for the chemokine CXCR4 receptor, the T-cell differentiation antigen, CD45, and the sodium-hydrogen exchanger-3, among others ( Table 1 The proline-specific peptidases

Die Zufuhr von Vorstufen von Glutathion durch Ernhrung kann helfen, die Glutathionspiegel im Krper zu erhhen und chronischen Erkrankungen entgegenzuwirken

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