By blocking NNMT activity, it increases critical cellular metabolites (SAM, NAD) that drive downstream increases in energy expenditure and metabolic health 1-4
A comprehensive review in Sexual Medicine Reviews found that "results of clinical studies mainly using intranasal oxytocin in men and women did not appear to confirm the facilitatory role found in animals" (PMC8509000)
Furthermore, although significant group-level differences in GABA and CBF were observed in our human studies even after controlling for sex, the higher prevalence of PTSD in women and potential sex-based neurobiological differences may influence treatment efficacy
General wellness and longevity Some researchers use GHK-CU as a general longevity compound based on its broad gene expression effects favoring tissue maintenance and repair
doi:10.1016/S0140-6736(21)01324-6 191
Chen Y, Liu K, Shi Y, Shao C