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The FDA has raised safety concerns about certain routes of administration for glutathione, particularly inhaled and high-dose intravenous forms
However, metformin can cross the placenta into the fetus, which has raised concerns about its safety and potential adverse effects
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Journal of Molecular Liquids
In fibrotic diseases, TGF- was upregulated and activated, which regulated fibroblasts phenotype and function, inducing myofibroblast and promoting the deposition of extracellular matrix 8
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