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It has been shown to modulate key longevity regulators like AMPK and SIRT1, which in turn orchestrates a pro-longevity program of enhanced cellular repair, improved stress resistance, and reduced inflammation
Many find it effective compared to others, with no need for additional supplements
Others require continued 12mg dosing to prevent regain
10.1124/mol.107.034058 131
Phase 3 data may narrow or widen the apparent efficacy gap
n = 5 mice (OSKM
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