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The patients were symptomatic with quiescent disease, meeting all of the following criteria: symptomatic (ileo-) colonic CD or UC

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Whereas much of the current attention surrounding GLP-1 RAs, or glucagon-like peptide-1 receptor agonists, has been focused on their unexpected and potent effect on weight loss, one important aspect of this class of drugs should not be overlooked: GLP-1 RAs have been shown to reduce the risk of heart attack, stroke, and other major adverse cardiovascular events (MACE) in patients with type 2 diabetes who have or are at high risk for atherosclerosis

Type 2 diabetes mellitus (T2DM) accounts for approximately 90% of cases of diabetes mellitus

Cardiovascular Outcomes Trial of Semaglutide in Patients with Type 2 Diabetes Mellitus SUSTAIN 6 (NCT01720446) was a 104-week, double-blind trial in which 3,297 patients with type 2 diabetes and high risk of cardiovascular events were randomized to semaglutide 0.5 mg once weekly, semaglutide 1 mg once weekly, or placebo in addition to standard-of-care