Recent reports indicate that ROS produced during liver transplantation were transferred to neighboring cells through Cx32 channels, aggravating oxidative stress and inflammation (Huang et al
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Thirdly, systematic factors such as hormone alterations and changes in metabolism contribute to a loss of muscle mass
In contrast to other GPxs, GPx4 is the only one that reduces the hydroperoxides of lipoproteins and complex lipids, such as cholesterol, cholesterol esters, and phospholipids [108], to protect mitochondrial ATP generation from oxidative damage [109]
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