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doi: 10.1002/ejhf.1596 65 SolomonSDMcMurrayJJVClaggettBde BoerRADeMetsDHernandezAFet al
doi: 10.1002/path.5056 81 BoccardiVMuraseccoIMecocciP
Tirzepatide mimics two hormones (GLP-1 and GIP)
Weight-loss: In a study of individuals who were on Saxenda for one year, 73% lost at least 5% of their starting body weight (10-pound weight loss for a person who weighs 200 pounds), and 41% lost at least 10% of their initial body weight (20-pound weight loss for a person who weighs 200 pounds)
The amino acid sequences of native GLP-1, exendin-4, xGLP, and xGLP-E4 are shown in Table 1
In addition, Ozempic and Mounjaro have FDA approval for type 2 diabetes blood sugar control but are often prescribed off-label for weight loss
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