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Uses, dosage, & side effects

Nicholas, S., Yuan, S

11.8% at 2.4 mg vs 2.3% placebo (68 wk) 9.5% to 20.1% across dose arms vs 0.4% placebo (48 wk) Tolerability signal Mostly gastrointestinal nausea, vomiting, diarrhoea, constipation

7 Underlying mechanisms include obesity-related comorbidities (T2DM, cardiovascular and renal diseases), immune system impairments facilitating a systemic diffusion of infection, increased type 2 inflammation with effects on the lung parenchyma, raised IL-6 levels, and abnormal secretion of adipokines and cytokines inducing low-grade inflammation

How is the dose of vitamin B12 injections adjusted for individual patients

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