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The S1P-S1PR1 pathway promotes CD4 + T cell differentiation into Th1/Th17 cells but has a negligible effect on the cytotoxic T lymphocyte activity of allogeneic CD8 + T cells

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Mice were euthanized by cervical dislocation, and the tumor were removed for weighing and volume measurement at endpoint

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Concentrations were determined in n = 2 replicate values

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