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Members of the Bcl-2 protein family are regulated through pathways influenced by estradiol, such that tumour cell expression of oestrogen receptors directly controls Bcl-2 levels (55, 56) Bcl-2-associated athanogene-1 (Bag-1), a Bcl-2-associated athanogene, functions as an anti-apoptotic protein by interacting with Bcl-2

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doi:10.1186/1471-244X-4-25 Rybicka I, Krawczyk M, Stanisz E, Gliszczyska-wigo A

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TGF-beta increases retinal endothelial cell permeability by increasing MMP-9: possible role of glial cells in endothelial barrier function