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Because GHK-Cu is naturally present in the body, serious adverse effects are uncommon when used under medical supervision at appropriate doses

According to a study, vitamin B12 deficiency is common but is more significant on strict vegetarians or vegans, and more people today are reaching for supplementation

Following reconstitution in sterile bacteriostatic water, the solution should be held at 4 C and used within 7 to 10 days

Category 2 significant safety concerns

As dose increases, homeostasis is achieved, and the bottom of the U-shaped dose-response curve is reached

The simultaneous upregulation of TIMP-1 and TIMP-2, the natural inhibitors of MMPs, suggests a regulatory influence of GHK-Cu on the balance between matrix synthesis and matrix degradation (Pickart et al., 2015)