Current clinical trials and future studies should take into account gender-dependent factors, receptor polymorphism, and the selectivity of brain regions in order to optimize the translational potential of this strategy [114]
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After filtering to retain participants with information regarding pre-treatment and post-treatment BMI and genotype data passing quality control, we obtained 4,889 participants, of which 3,948 had complete data when incorporating covariates akin to those used in the GWAS
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