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Arch Med Res 34(2):8999
The long half-life means that it takes approximately 4 to 5 weeks to reach steady-state concentrations, and similarly, it takes several weeks for the drug to be fully eliminated from the body after discontinuation
This can cause nausea, vomiting, and not getting enough nutrients
When dark urine does occur in Ozempic users, it most commonly appears during these initial weeks or following dose increases
Additionally, it shows a greater ability to inhibit tyrosinase activity (an enzyme that produces melanin and causes hyperpigmentation) than other antioxidants used in skin care, such as kojic acid 2
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