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Weight Loss Drug Comparison: Efficacy, Muscle Loss, and Market Stage Towards a Dual-Action Approach: Fat Loss and Muscle Preservation Recognizing the need for a more balanced approach to weight management, pharmaceutical innovators are now focusing on therapies that not only promote fat loss but also preserve or enhance muscle mass (Rodgers and Christopher 2022)
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Suppression of diacylglycerol acyltransferase-2 (DGAT2), but not DGAT1, with antisense oligonucleotides reverses diet-induced hepatic steatosis and insulin resistance
Side effects can include nausea, constipation, dizziness, and an increased risk of mood changes or suicidal thoughts, particularly in individuals with a history of depression or psychiatric illness
If weight loss has plateaued or appetite suppression weakened, increase to 75 units (7.5 mg)
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