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Another network meta-analysis of RCTs, including participants with T2DM, found that GLP-1 RAs decreased the risk of non-fatal MI (Odds Ratio [OR] = 0.92, 95%CI = 0.850.99) when compared to placebo or standard care ( Unstable angina pectoris: An umbrella review of meta-analyses of RCTs including 56,004 patients with diabetes, prediabetes, and at high risk of diabetes, found no association between GLP-1 RAs and the risk of uAP (RR = 1.06, 95%CI = 0.931.21) when compared to placebo (Zhu et al., 2020)
What About Reserve and National Guard Considerations
Quality of life isn't a soft endpoint
Guideline Applicability This guideline applies to patients with A1C values between 6.5% and 9%
Do Glutathione Injections Have Any Side Effects: Glutathione is generally safe for most adults, but some risks of injection therapies include but are not limited to
Other GLP-1 medications: Mounjaro/Zepbound (tirzepatide), Trulicity, Saxenda, or others may be appropriate
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