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Additionally, a 2024 commentary in Nature Reviews Endocrinology suggested that the future of GLP-1 use may be individualized dosing , guided by biomarker response and patient goals

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The results were striking: Average total weight loss: up to 20.7% of body weight Around one-third of users lost 25% or more of their starting weight Data also showed that semaglutide 7.2mg was well tolerated , with a safety profile consistent with the 2.4mg dose and earlier semaglutide trials from Novo Nordisk This places Wegovy 7.2mg in the same league as Mounjaro 15mg in terms of outcomes

Acknowledgements We thank the School of Biomedical Sciences and CHIRI for financial support and excellent research facilities, respectively

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