Starting low and increasing on a schedule is what keeps side effects manageable and lets the satiety effect build
It is probably the beginning of a much broader shift
A 2007 double-blind, multicenter trial (n=102) showed ALC 1,500 mg/day significantly improved tender point count, total myalgic score, depression, and musculoskeletal pain compared to placebo.[9] A 2015 RCT found ALC 1,500 mg/day comparable to duloxetine 60 mg/day for pain and depression.[8] Most notably, a 2023 RCT demonstrated that adding PEA 1,200 mg/day + ALC 2,000 mg/day to ongoing duloxetine + pregabalin therapy produced significantly greater improvements in Widespread Pain Index, FIQR, and FASmod scores.[7] Role in Treatment: ALC can be used as monotherapy or adjunctive therapy in fibromyalgia
The included studies were conducted in 10 Countries across 5 continents (6 studies from Turkey
(6) However, some people will never test positive for thyroid antibodies, yet may have full-blown Hashimotos, with all the symptoms associated with it
Next, confirm that a licensed U.S