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Baseline EKG once in healthy adults over 40 or sooner if risk factors are present

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Discussion In this mechanistic analysis of the SUMMIT trial, we found that, compared with placebo, treatment with the long-acting glucose-dependent insulinotropic polypeptide receptor and glucagon-like peptide-1 receptor agonist tirzepatide reduced BP and estimates of circulatory volume expansion in patients with obesity-related HFpEF

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The weight maintenance guide covers this transition in detail