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Semax increases BDNF expression in targeted regions relevant to mood, including the hippocampus and prefrontal cortex, the very areas where BDNF deficits are most pronounced in depressed individuals

A study performed by Yang and Wang in 2009 showed in-vivo study that pyridoxine can inhibit glutamate release from cerebrocortical synaptosomes by suppressing voltage-dependent Ca2+ entry

Maintenance at 2mg weekly reduces costs to roughly $60-130 monthly

Bacteriostatic water contains 0.9% benzyl alcohol as a preservative, which inhibits bacterial growth in multi-dose vials for up to 28 days after first puncture

Unlike other treatments that target the vascular system, PT-141 directly affects the central nervous system, leading to improved sexual desire and arousal without affecting blood pressure