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Psychiatry 62 , 14231430 (2007)

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Preliminary clinical studies suggest CoQ10 (300400 mg/day) improves fatigue and sleep disturbances, but larger trials are needed for confirmation

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This has also been underpinned by the Dutch Health Council, which has indicated no upper intake limits for these substances (2003) and by the Dutch Tuchtraad ( Disciplinary Board) in 2011, when a GP was sued for having prescribed B12 injections (once a month) for a diagnosed B12 deficiency after gastric bypass surgery

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The production of GSSR, instead, requires a reactive cysteinyl residue, which at physiological pH is present in the thiolate form

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