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Specifically, wild-type p53 expression can decrease the expression of PDL1 by increasing the expression of miR34a and promoting the expression of the natural killer (NK) cell-activating ligands UL16-binding protein 1 (ULBP1) and ULBP2

All optimized cut-off value were selected based on the Youden Index (YI) and were provided in Supplementary section

By inhibiting this interaction, FOXO4-DRI allows reactivation of the apoptotic pathway in non-proliferative senescent cells, leading to their selective elimination without damaging healthy tissue

& Prentki, M

M.HoersterF.LindnerM.KriegbaumH.EngelmannG.et al (2009)

Factors affecting the degradation and drug-release mechanism of poly(lactic acid) and poly[(lactic acid)-co-(glycolic acid)]