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Hormonal imbalances : Hormonal fluctuations due to menstruation, PCOS, and even pregnancy can lead to an increase in sebum production
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The hypermethylation of progesterone receptor (PGR) gene in luteal cells leads to receptor expression loss which impairs hormone response and breaks down the regulatory feedback needed for sustained hormone production (184)
Occludin functions as a dynamic regulatory protein whose presence at the BBB is correlated with increased transendothelial electrical resistance and decreased paracellular permeability
LGG reduces oxidative stress-induced damage by enhancing endogenous antioxidant enzyme production, including superoxide dismutase (SOD) and glutathione (GSH), while simultaneously suppressing ROS generation
These results support that HEXB recruit macrophages through ITGB1 receptor on macrophages
