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Its the combination of three amino acids: glutamate, glycine and cysteine
Some GLP-1 receptor agonists, particularly exenatide extended-release formulations, commonly cause small nodules at injection sites
A multidisciplinary expert consensus on managing GI side effects with GLP-1 medications recommends gradually increasing fiber once initial GI symptoms improve, rather than frontloading it
A comprehensive physical exam should also be performed to assess for other possible causes of symptoms, such as thyroid dysfunction or fibroids, which can mimic perimenopausal symptoms
Managing this effectively requires understanding the complete gastrointestinal picture, not just treating the symptom in isolation
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