Penney, J., Ralvenius, W
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Addiction From Gatorade to Addiction and GLP-1s Neuroscience and the gut-brain revolution in obesity and addiction medicine
Clin Exp Heal Sci 12:576581
This research peptide has attracted extensive scientific interest for its observed activity in a wide range of in vitro and animal model studies involving tissue repair mechanisms, cellular migration, and angiogenesis signaling pathways
An extensive list of agents including thiazolidinediones, insulin-like growth factors, fibroblast growth factors, gastrin, glycogen synthase kinase-3 (GSK-3) inhibitors, protein kinase dual-specificity tyrosine-phosphorylation-regulated kinase 1A (DYRK1A) inhibitors, gamma-aminobutyric acid, quinolones, sphingosine phosphate, oestrogens and phytoestrogens, polyphenols, flavonoids and other plant compounds has been reported to increase beta cell proliferation in vitro or in animal models, but specifically targeting these agents to pancreatic beta cells in vivo remains an unfulfilled therapeutic challenge [30]