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No human pharmacokinetic data exists to confirm whether these doses translate to effective systemic exposure

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Both groups reached the same maintenance dose, but the escalated group achieved greater weight loss (-17.1% vs -15.7%) with fewer gastrointestinal adverse events

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Cons of Injections Requires Medical Supervision: You need a prescription and a qualified professional to administer the shot

10.1016/j.neubiorev.2020.10.017 Neurosci Biobehav Rev