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Clinical studies show no significant side effects with long-term daily use

In the STEP 1 trial which studied semaglutide in adults with overweight or obesity, researchers studied body mass composition as a secondary endpoint via DXA in a subpopulation of trial enrollees randomized to treatment or placebo

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Hyperpigmentation Control: Glutathione may help regulate melanin synthesis, making it beneficial for controlling hyperpigmentation issues

International Journal of Obesity , 47(2), 345-353

Chazelas P, Steichen C, Favreau F, Trouillas P, Hannaert P, Thuillier R, et al